After years and years of using a mouse with my right hand, I have decided I need a change. Actually, it has more to do with the feeling that my right arm is getting unduly stressed and potentially vulnerable to RSI. In any case, I have decided to switch hands for mouse-using.
It is hard. Especially since most mice are built for the non-sinister hand. However, Logitech does make the MX610, a left-handed wireless mouse. I just put in my order, and look forward to learning to use my off-hand for mousing.
For those of you naturally southpawed, you might want to check it out. Or for those of you interested in trying out a new perspective without going too crazy and getting a motorcycle, or something.